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As a complementary agent to incretin-based therapies (GLP-1 agonists and GLP-1/GIP dual agonists), cagrilintide has attracted substantial research attention for its additive weight-loss effects when co-administered with semaglutide-class molecules (the investigational combination known as cagrisema)

Clinical evidence backed up these findings, with improvements in gamete quality trailing oxidative stress reduction

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evidence limited to preclinical animal and in vitro studies Semaglutide : Three FDA approvals across diabetes, obesity, and oral delivery