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Curr Atheroscl Rep

Since vascular growth is not only up-regulated but also accompanied by significant changes in their architecture (i.e., abnormal vasculature, disorganization, etc.) and function [129,130], a tumor burdened with those vessels may eventually be resistant to various therapeutic methods, including systemic treatment in the form of chemotherapy or radiotherapy [131]

J Biol Chem 291:2241422426

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Self-administering into the joint risks septic arthritis, which can destroy cartilage within 24-48 hours