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This may be inconvenient for some patients

Effect of oxyntomodulin, glucagon, GLP-1, and combined glucagon +GLP-1 infusion on food intake, appetite, and resting energy expenditure

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Additionally, GLP-1 receptor agonists slow gastric emptying, which may be beneficial in some post-surgical patients

The injection is subcutaneous given under the skin, usually in the abdomen, thigh, or upper arm