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In a multicenter study of 146 patients with painful DPN for 1 to 5 years and a pain score of 40 mm on the Short-Form McGill Pain Questionnaire or an ADP score of 4 on an 11-point pain numerical rating scale (NRS), pregabalin significantly reduced the mean pain score compared with placebo (pregabalin, from 6.5 to 4.0
Designing these solutions is extremely non-trivial
Some have a wingspan of up to 3 meters (10 feet)
In contrast, endogenous antioxidant systems are a complex and compartmentalized network that involve controlled and localized production of specific ROS [54]
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Injectable administration is hypothesized to provide systemic distribution, but human pharmacokinetic data for this route does not exist
