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This can stimulate inflammatory pathways, leading to the phosphorylation of the IkappaB alpha protein and the production of inflammatory cytokines (35)

A meta-analysis of randomized controlled trials (RCTs) including patients with HF found no improvement in hospitalization rates or echocardiographic parameters such as LVEF or LV end-systolic or diastolic volume

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Most of the peptides exhibit a cationic charge combined with an amphipathic character

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