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Following the loading protocol, athletes can generally maintain stores with a daily maintenance dose of 3-5 grams per day." Jose Antonio, Ph.D., the co-founder of the International Society of Sports Nutrition, also labels the loading protocol "something you should definitely do" in his video "8 Questions About Creatine Answered." Con: Possible side effects

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(2) (3) When it does occur in animals, it is rare and associated with a vitamin C deficiency

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"Similarly, side effects like nausea can differ widely in both intensity and duration