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Moro T, Tinsley G, Bianco A, Marcolin G, Pacelli QF, Battaglia G et al (2016) Effects of eight weeks of time-restricted feeding in resistance-trained males

doi: 10.1016/0741-8329(86)90058-3

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The mechanistic basis for this synergy involves complementary intracellular signaling pathways: GHRH primarily activates the cAMP-PKA pathway to stimulate GH gene transcription and GH vesicle exocytosis, while GHS-R1a agonists primarily activate the IP3-calcium pathway to trigger rapid GH granule fusion and secretion