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Registration and protocol This review was registered on the Open Science Framework (OSF) registries prior to conduction ( Competing interests Dr Nicholas Chew is supported by the NUHS Seed Fund (NUHSRO/2022/058/RO5+6/Seed-Mar/03), National University of Singapore Yong Loo Lin School of Medicines Academic Fellowship Scheme, and NUHS Clinician Scientist Program (NCSP2.0/2024/NUHS/NCWS)

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