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Clinical Studies Supporting Ozempics Mechanism Several clinical studies have explored how Ozempic works in the body, offering scientific evidence behind its effectiveness for blood sugar control and weight loss

Figure 29: Photograph of Professor Catherine rskov, credit: rskov

Eli Lilly is also developing a drug called retatrutide, that targets three receptors (glucagon-like peptide 1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors)

Comparison of the effects of glucagon-like peptide receptor agonists and sodium-glucose cotransporter 2 inhibitors for prevention of major adverse cardiovascular and renal outcomes in type 2 diabetes mellitus

Some people find tirzepatide easier to tolerate, while others have a smoother experience on semaglutide a variability driven by factors like genetics, diet, and individual dose escalation protocols

J Nutr (2009) 139(9):161925