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Using Immunofluorescence techniques, the authors were able to show that macrophages that expressed mincle entered the damaged kidney on the third day after cisplatin was introduced

This case occurred during rapid dose titration of one of the danuglipron once-daily formulations being studied

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However, they work in different ways in the body

But the primary concern is the risk of ochronosis, a rare but challenging condition where long-term overuse paradoxically causes darkening of the skin, says Francesa Lewis, MD, a board-certified dermatologist in Delray Beach, Florida