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Sophie Dix (BSc, PhD) Published: 25 March 2024 | Updated: 6 February 2026 Updated: 6 February 2026 Reading time: 4 minutes Quick navigation: What are weight loss injections

8 A case-control study that compared 25,956 patients who had vitamin B 12 deficiency with 184,199 control patients found a significantly increased risk of vitamin B 12 deficiency in patients who had taken proton pump inhibitors (odds ratio = 1.65) or histamine H 2 blockers (odds ratio = 1.25) for at least two years

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This may be due to weight loss-related changes in thyroid hormone metabolism and distribution rather than a direct drug interaction