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The standard redox potential of the ascorbyl radical/ascorbate couple is 0.282 V, and that of the dehydroascorbate/ascorbyl radical couple is 0.174 V [14]

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in The Biological Effects of Glutamic Acid and Its Derivatives (ed

In Arabidopsis, arGST loss-of-function mutations were additionally linked with an increased content of flavonols 19,45 , most probably due to a second oxidation of accumulating flavan-3,3,4-triol ( 4 ), which is catalysed by At LDOX in vitro 11,12,13

Despite some uncertainty around the topline readout and side effect tolerability, Boehringer's ongoing phase 3 trials may soon provide more conclusive evidence