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Patients with a history of thyroid C-cell tumours should not use Wegovy

But GLP-1 receptors are also found on cells throughout the body, including the heart, immune system, blood vessels, and several brain regions

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Berberine inhibits pathogenic species such as f_Erysipelotrichaceae and Alistipes and increases the abundance of SCFA-producing bacteria including Alloprevotella and Flavonifractor

Research interest focuses on signalling coordination, receptor-specific activation, and pathway timing rather than prolonged or isolated pathway engagement