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P53 can inhibit cysteine uptake by downregulating SLC7A11, reducing GPX activity and GSH synthesis and subsequently causing intracellular ROS accumulation and ferroptosis (83)

MC3R and MC5R activity has been investigated in the context of metabolic regulation and exocrine gland function respectively

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The regulatory pathway for biomarker approval adds additional complexity and delay to clinical implementation (Nisenblat et al., 2016)

Treatment of membranous nephropathy by disulfiram through inhibition of podocyte pyroptosis

The two terms refer to the same molecule