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Signs include hives, swelling of the face, lips, or throat, and difficulty breathing
In supervised studies with the GHRH analog tesamorelin, IGF-1 stayed within the age-normal range, and insulin-stimulated glucose uptake was preserved (Stanley et al., 2011)
Additionally, research into ALS (amyotrophic lateral sclerosis) suggests that MSCs may be a feasible treatment, providing hope for diseases marked by progressive muscle deterioration
HA integrity has also been shown to critically modulate TGF--driven fibroblast differentiation, as enzymatic fragmentation suppresses -smooth muscle actin (-SMA) and collagen type I expression, emphasizing the importance of balanced HA turnover for proper ECM remodeling and scar resolution [9]
