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MC3R/MC4R (Neuroendocrine/Metabolic): Explore appetite regulation , energy homeostasis , and sexual-function signaling in preclinical systems

doi: 10.1016/j.freeradbiomed.2024.01.029 79 SahaKFisherMLAdhikaryGGrunDEckertRL

& Mller, M

Compare injectable vs oral peptide delivery to understand the bioavailability differences

Peptide therapy may have side effects such as increased appetite, elevated blood sugar levels, fluid retention, and decreased insulin sensitivity depending upon a patients underlying health conditions

Studies have used doses ranging from 100 million to 10 billion CFU daily, with beneficial effects observed across this range