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Those taking a placebo were only expected to lose 1-2% of their body weight

If youre trying to lose weight, exercise compliments GLP-1s by helping us burn calories, reduce fat mass and preserve lean muscle mass, which helps us burn more calories

With respect to exercise, that usually involves at least 30 minutes of exercise cardio and weight/resistance training most days of the week

Smaller, more frequent meals are generally better tolerated than large ones because GLP-1 medications slow gastric emptying

This structured lesion assessment supported severity classification and ensured consistency across visits and longitudinal comparisons, rather than serving as an independent outcome measure

In vitro study found that topiramate increased MDA, NO and ROS production in astrocytes, showing a dose-dependent negative effect (Pavone and Cardile, 2003)