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Projected Users and Market Size Evolution Numerous analysts have published projections on the future use of GLP-1RAs, with all forecasting demand to grow significantly, driven by a combination of factors that include: Increasing Prevalence of Obesity: The number of people living with obesity (BMI of over 30) has tripled since 1975 to c.760m people in 2020

Translating oral GLP-1 innovation into scale places unprecedented demands on operational execution across the pharmaceutical value chain