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Patients with active inflammation, recent flares, severe malnutrition, strictures, or unstable medication regimens should generally avoid GLP-1 initiation until disease control improves

(2010) in the BBB of mice

Therefore, future longitudinal studies integrating clinical and preclinical approaches are warranted to elucidate the mechanistic interplay among various components of excitatory glutamatergic transmission across the lifespan of individuals with ASD