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Strengths and Limitations The current study used robust registry data and novel methodology to describe the high disease burden that is often experienced by patients with psoriasis, regardless of their level of BSA involvement, at the time of initiation of biologic therapy

CagriSema-class data (Frias et al., 2023) demonstrated 15.6% weight loss at 32 weeks for the cagrilintide+semaglutide combination, with a curve trending well beyond what either monotherapy achieved directly motivating the Tirzepatide + Cagrilintide stacking protocols now in use

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