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intravenous administration of glutathione are generally not practical for increasing circulating glutathione for most individuals because this procedure is expensive, requires regular visits to a medical practitioner's office, is unsuitable for children and many adults, and poses the risks of side effects associated with regular injections

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The evolutionary distances were computed using the Poisson correction method and are in the units of the number of amino acid substitutions per site 43

Aydin et al., 2000)