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Treatment risks included weight gain (none, 5%, 10%), added risk of skin rash (none, 10%, 20%), and risk of liver damage (none, 1 in 1000, 10 in 1000)

First, appetite feedback increases after weight loss, driven by coordinated neuroendocrine adaptations, receptor-level changes, and recalibration of the brains reward circuitry [16,17,18,19,20]

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Certain detrimental effects on a childs health are strongly correlated with maternal obesity and gestational diabetes underscoring the need for a safer and more efficient drug (89)