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Sleep pattern disruptions and vivid dreams are occasionally reported

The basic principle causing the radiation-induced toxicity is the excessive generation of reactive oxygen species (ROS) due to the radiolysis of cellular water, which in turn oxidizes the critical biomolecules such as lipid, protein, and DNA [36,37,38,39]

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This effect was mediated through the maintenance of intestinal barrier integrity and suppression of the TLR4 signalling pathway, as confirmed using Tlr4 knockout mice