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At week 40, the difference between the top and bottom quartiles was an additional 8.3 lbs of weight lossabout 25% more weight lossfor the most highly-engaged group

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Tesamorelin gained FDA approval in 2010 specifically for reducing visceral adipose tissue in HIV-associated lipodystrophy, with clinical trials showing 1518% reductions in visceral fat after 26 weeks at 2mg daily dosing