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Briefly, the mice were anesthetized with an overdose of 1.25% tribromoethanol (0.2 mL/10 g body weight), and then euthanized by cervical dislocation in accordance with AVMA guidelines 26,27

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14,16 High iodine intake has been shown to provoke autoimmunity in animal models with a predisposition, and this corroborates the epidemiological data demonstrating a high incidence of Hashimotos thyroiditis and earlier onset of Graves disease in regions of high iodine intake

doi: 10.1507/endocrj.k07e-130 12 ShinYSYouJHChaJSParkJK