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Objective response rate among patients with locally advanced or metastatic sarcoma treated with talimogene laherparepvec in combination with pembrolizumab: A phase 2 clinical trial

It has been suggested that gut archaea, similar to gut bacteria, may produce beneficial metabolites such as SCFAs, tryptophan derivatives, GABA, and deconjugated bile acids

Mild side effects may occur frequently with dose increases but become less noticeable over time 5

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In this study, the abundance of immune cells was not strongly associated with the expression of TCA-related genes but was strongly positively correlated with the activity of the respiratory chain complex

Fatigue: Some individuals may feel tired or lethargic, particularly during the initial stages of treatment