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Eli Lillys retatrutide, a triple agonist targeting GLP-1, GIP, and glucagon receptors, remains in Phase 3 TRIUMPH trials as of mid-2026, with NDA submission projected no earlier than Q4 2026

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In addition, GLP1-RAs demonstrate numerous cardiovascular protective effects in subjects with or without diabetes

Secondly, whether lean MASLD patients can benefit from GLP-1RA-related weight loss

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