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Heffron and his team, however, had begun their study a year earlier

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Initial small trials from 2016 to 2017, including EXSCEL, FIGHT, and LIVE, were not supportive of the use of GLP-1RAs in HFrEF with negative outcomes related to cardiovascular events [53,54,55]

Earlier research had potentially linked these drugs -- which are used to treat type 2 diabetes and obesity -- with suicidal thoughts and self-harm, researchers added

That was a no-go for P.B

Special considerations : If you require any procedures involving anaesthesia or sedation, inform your healthcare team that you are taking Mounjaro, as delayed gastric emptying may affect procedural planning