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Consistent, controlled dosing

(2020) align with our observations

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[1] Some compounders suggest adding B12 to tirzepatide formulations based on theoretical concerns about vitamin B12 absorption, though it's important to note that clinical evidence specifically linking tirzepatide to B12 deficiency is lacking

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For example, when using RSL3a canonical ferroptosis inducer through inhibition of GPx4GPx1 cannot compensate for the loss of GPx4 since its main substrates are hydroperoxides whereas GPx4 reduces lipid peroxides [19]