[65] found that Liras stimulation of liver FGF21 expression may require the expression of GLP-1R in extrahepatic organs, and the increase of liver FGF21 is also necessary for Lira to improve hepatic lipid homeostasis
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Moreover, reduced expression of uterine receptivity markers, for example, integrin, HOXA10 and IGFB1, and increased expression of inflammatory factors, such as TNF and NF-B, contribute to increased cell proliferation in PCOS 134,136,137
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