In trastuzumab-resistant Her2-positive breast cancer cells, IGFBP-3 expression was reduced, leading to the inhibition of Wnt signaling pathway release and increased Cullin7 expression mediated by TCF7L2
Mol Cell Biochem 396:269280 Arya A, Kumar S, Paul R, Suryavanshi A, Kain D, Sahoo RN (2021) Ethnopharmacological survey of indigenous medicinal plants of Palampur, Himachal Pradesh in north-western Himalaya, India
Mechanism Although the biological rationale for GLP-1 RA-induced biliary toxicity is not clear, the current findings indicate potential weight-loss-dependent mechanisms
Liraglutide (Saxenda) Saxenda received FDA approval on December 23, 2014 as the first GLP 1 receptor agonist specifically indicated for chronic weight management
The global burden of chronic kidney disease and the way forward
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