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Tumor-targeted anti-VEGF RNAi capable of sequentially responding to intracellular microenvironments for potent systemic tumor suppression
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PMID: 29756566 View source Malinda KM, et al
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Human data remain limited and mixed, with dose, timing, and sex as key variables
In addition, differences in corresponding changes in expression levels of genes associated with dendritic cell maturation, interferon signaling, and NF-B signaling pathways in circulating T cells and monocytes have been noted (Jangi et al., 2016)
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