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Rapid caloric restriction can affect serotonin production, since the amino acid tryptophan (a serotonin precursor) comes from dietary protein

Rotation between sites helps prevent localized skin reactions and ensures consistent absorption

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What can help: Because Contrave contains bupropion (an antidepressant), your doctor will likely taper the dose to avoid withdrawal symptoms

Some users express that the results were slower than anticipated or less pronounced than expected

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