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Therefore, in states of chronic under-nutrition, hepatic GH resistance is an adaptive response, as high GH levels are necessary to maintain euglycemia, while low IGF-I levels conserves energy during periods of nutritional deprivation

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Any form of thyroid unbalance can disrupt its function and quickly manifest symptoms such as fatigue, changes in metabolism and weight gain, constipation, and even dry skin

Major enzymatic and non-enzymatic antioxidants (Adapted and modified from [56])

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