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Here, the currently inhibited pulmonary GPX4-dependent ferroptosis pathways will be reviewed

10.1007/s00213-022-06225-2 87 MorozN.TongM.LongatoL.XuH.DE LA MonteS

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Enzymatic Cofactor Activity : Serves as an essential cofactor for glutathione peroxidase and glutathione reductase enzymes, enabling these protective systems to neutralize hydrogen peroxide and lipid peroxides that would otherwise damage cellular membranes

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Additionally, metabolic rates tend to slow with age, and men often have faster rates than women