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Science 2005;310:17826

[70] demonstrated that the phosphorylated STAT3 proteins interacted with the phosphorylated FoxO1 and FoxO3a proteins in the cytoplasm of mouse CD4 + T cells and subsequently promoted the import of the complex into nuclei where the dephosphorylated FoxO proteins transactivated specific genes

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27 While we await outcomes of the FOCUS trial, which is dedicated to assessing the effects of semaglutide on eye health, patients using subcutaneous semaglutide should be counselled about the increased risk of retinopathy

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