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The results of these randomized, placebo-controlled studies showed that intravenous lipoic acid could improve endothelial function in patients with impaired fasting glucose (64) or impaired glucose tolerance (65)

PMID: 35658024 Jastreboff AM, et al

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1,2 In a 2005 Cochrane review, patients who received high dosages of oral vitamin B 12 (1 to 2 mg daily) for 90 to 120 days had an improvement in serum vitamin B 12 similar to patients who received intramuscular injections of vitamin B 12