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The results showed that compared with the RBITC-GLP-1RAs@NPs group, the fluorescence intensity in the kidney was lower on the first day in the rats injected with RBITC-GLP-1RAs@NPs-WYRGRL, while the fluorescence intensity in the lower limb joints was significantly increased

These findings underscore the importance of distinguishing between metabolic therapies that actively modulate neuroprotective pathways, such as metformin, and those that primarily function through systemic appetite suppression

The gold standard involves HPLC (High-Performance Liquid Chromatography) testing combined with mass spectrometry, conducted by an independent laboratory with no financial ties to the vendor

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FASEB J 2001

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