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Since the total number of CY 2024 single frequency claims for CY code 0686T surpasses the 99 claim threshold for the universal low volume APC policy, we would use the geometric mean cost of the CY 2024 claims data to set the payment rate for CY 2026 under our standard ratesetting methodology, rather than the highest of the three statistical methodologies over a 4-year lookback period

Thyroid function should be checked at baseline and monitored during treatment

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Future studies should explore the dynamic interactions among SIRT1, mTOR, autophagy, and endoplasmic reticulum (ER) stress to elucidate its regulatory functions under varying metabolic states, guiding the development of targeted interventions for early-stage MASLD-related metabolic disorders

Specific primary antibodies were shown in Table 2, and horseradish peroxidase-conjugated goat anti-mouse or anti-rabbit IgG secondary antibodies (1:4000