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Nakashima J, Tachibana M, Ueno M, Miyajima A, Baba S, Murai M

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3.2 Carnitine deficiency across the course of diet therapy Of the 47 patients with a normal free carnitine level at baseline prior to starting MAD, 18 (38.3%) patients developed free carnitine deficiency during the course of diet therapy

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The authors inferred that the increased plasma Met concentration in the RPM group, likely supplied the elevated demand in the mammary tissue required to synthesize cytoprotective proteins, such as heat-shock proteins, which are necessary for cellular defense against thermal stress (Pate et al., 2021)

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