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The GHRH signal (sermorelin) tells the pituitary to release GH, while the ghrelin signal (ipamorelin) both adds a second release stimulus and lifts somatostatin's inhibitory brake

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doi: 10.1016/j.ando.2010.06.006 208 CaturegliPDe RemigisAChuangKDembeleMIwamaAIwamaS

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