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11,239 It is also possible that GLP-1 therapies mediate beneficial actions via extra cardiovascular GLP-1 signalling, as one study reported that exendin-4 administration in rat femoral arteries did not affect short-term triglyceride exposure-induced endothelial dysfunction

Several small molecules and protein-based compounds are under development to modulate GPX4 enzyme activity

Glutationul (glutationa) este considerat a fi principalul antioxidant neenzimatic

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Ultimately, the personalized integration of these strategies into treatment regimens tailored to each patient may be an important direction for future treatment