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It is preferable to use combination therapies having complementary mechanisms of action that target different pathways addressing the multiple pathophysiologic abnormalities of T2DM [10,11,12]

Diagnostic value of serum high molecular weight alkaline phosphatase in early detection of cholestatic jaundice in neonates

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Nakagawa, K., Kiko, T., Miyazawa, T., Burdeos, G

This study not only shows that urate transports play considerable roles in the progression of hyperuricaemia-associated diseases but also indicates that they may be used as therapeutic targets