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Tirzepatide currently has a better-established safety profile due to years of real-world use and multiple large trials

Likewise, the PIONEER trials established that between oral semaglutide and placebo, there was a 53% decrease in cardiovascular mortality

According to the Wegovy Summary of Product Characteristics (SmPC), the mechanism of action involves binding to GLP-1 receptors, slowing gastric emptying, reducing hunger signals, and promoting feelings of fullness

From a treatment point of view, there are clear differences

Randomized controlled trials (RCTs) of antioxidant supplementation that evaluate memory functions are needed to evaluate this hypothesis

Glutamatergic system dysfunction lies at the root of neurotransmitter dysfunction in ASD