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Each week, the injections got easier

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To overcome the limitations of first-generation inhibitors, next-generation autophagy inhibitors such as Lys05 and DQ661 have been developed

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The close interrelationship between MASLD and T2DM creates a self-perpetuating vicious cycle that amplifies the risk of both hepatic and extrahepatic complications, including fatal and nonfatal CVD events and chronic kidney disease, which are major causes of morbidity and mortality in this patient population (as summarized in Figure 3(Fig