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Data availability The DNA methylation data generated in this study for longitudinal semaglutide and placebo samples, have been deposited in the GEO database under accession number: GSE327270

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The peptide also supports the growth and development of new brain cells by increasing specific markers like Nestin and GAP43 in human stem cells (4)

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Accordingly, in experimental models, supplements of omega-3 PUFAs have been demonstrated to exert neuro-protective and cardio-protective effects against hypothyroidism-induced damage, while attenuating hyperthyroidism-associated complications, including arrhythmias and hepatic dysfunction, thereby conferring protective actions on peripheral tissues across opposing states of thyroid dysfunction [127,130,131,132]