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Erratum in: Nature

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Tirzepatide is a dual incretin receptor agonist, meaning it activates both the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor

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An unusual feature reported in the literature is timing: in some studies, DSIP given during the day was associated with improved sleep that night , rather than acting as an immediate, bedtime sedative

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