Conversely, while certain trials exploring CB-839 alone or in combination with other therapies have exhibited less auspicious results, the potential value of CB-839 as a complementary component to existing treatment paradigms persists [218]
The expansion-era literature continues to add depth to the compound's research profile
Overall, these findings indicate that although intracellular GSH does not affect tumour growth and survival, extracellular GSH is highly abundant and potentially supports tumour growth
J., Hackett, S
Acta Physiol (Oxf) (2011) 201(1):1516
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