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A SerHisAsp triad has been proposed to facilitate thiolate formation at Cys248, enabling nucleophilic attack on the sulfur atom of 3-mercaptopyruvate (Figure 7) (Yadav et al., 2013)

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In our study, L-carnitine administration significantly reduced the post-operative level of the apoptotic cell-death markers (fas and caspase-3) compared to the control group, which is in agreement with the results of Li et al