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KPV inhibitsNF-B activation at nanomolar concentrations through stabilization of IB- and prevention of p65RelA nuclear translocation[13]

The chlorogenic acid lactones are less polar than their parent compounds and should be more permeable to the blood-brain barrier

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The researchers observed significant and consistent increases in neuronal activity just minutes following intranasal administration, finding that at least the first peak of activity was linked to epithalons direct action on cortical cells [3]

These outcomes describe research observations, not clinical performance